Results Derivation of Genetic Risk Scores Of the 6 well-studied variants, the associations with IS were nominally significant regarding 4 variants (rs6843082 [ PITX2 ]; rs2383207 [ CDKN2B - CDKN2A ]; rs2107595 [ HDAC9 ]; and rs879324 [ ZFHX3 ]) in our derivation samples (Tables I and II in the online-only Data Supplement ).
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