Cbl-b Deficiency Mediates Resistance to Programmed Death-Ligand 1/Programmed Death-1 Regulation.

Although it did not reach statistical significance, PD-L1 Ig reduced the IFN-γ expression of WT NK cells based on the MFI, while that of Cbl-b −/− NK cells was not reduced by PD-L1 Ig (Figure 5 D).

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