P2Y<sub>2</sub> receptor modulates shear stress-induced cell alignment and actin stress fibers in human umbilical vein endothelial cells.

Although, the observation of reduced shear stress-mediated AKT activation did not reach statistical significance in cells expressing the P2Y 2 RGE mutant receptors, we found a significant decrease in eNOS activation, as compared to cells expressing the P2Y 2 RGD WT receptor.

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