Surprisingly, it appears that Ti particles induce a slightly higher percentage of M2 macrophages than the Control group, although the difference did not reach statistical significance; this may be the feedback of M1 macrophage activation but the exact mechanism requires further investigation.
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Curcumin Attenuates Titanium Particle-Induced Inflammation by Regulating Macrophage Polarization <i>In Vitro</i> and <i>In Vivo</i>.
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