Those combined vaccine groups showed a trend of lower virus titers compared to IIV alone vaccinated chickens, especially at 3 DPC but no significant difference was observed between the prime-boost (IIV, M2eP) and single (IIV-4w) or combined (IIV+M2eP) vaccines administered at 4 weeks of age.
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Supplementation of inactivated influenza vaccine with norovirus P particle-M2e chimeric vaccine enhances protection against heterologous virus challenge in chickens.
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