<i>PITX3</i> DNA methylation is an independent predictor of overall survival in patients with head and neck squamous cell carcinoma.

Clin Epigenetics · 2017 · PMC5290668 · PMID 28174607

Europe PMC DOI

hedged sentence

0.0610

closest p · 1.2× alpha

0.0610

boldest claim

The sentences

a strong trendp = 0.061so close (0.05 < p ≤ 0.1)

Association of PITX3 DNA methylation with survival Higher PITX3 DNA methylation analyzed as continuous variable showed a strong trend towards poorer overall survival in the training cohort (Hazard ratio (HR) = 1.01, [95% confidence interval (95%CI) 1.00–1.02], p = 0.061).

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