Is investigator background related to outcome in head to head trials of psychotherapy and pharmacotherapy for adult depression? A systematic review and meta-analysis.

PLoS One · 2017 · PMC5291442 · PMID 28158281

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

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boldest claim

The sentences

a borderline significant trendp = 0.06so close (0.05 < p ≤ 0.1)

In a similar vein, trials where the last author was a statistician/other technical as contrasted to those where he/she was a psychiatrist/MD showed a borderline significant trend of favoring pharmacotherapy (b = -0.26, 95% CI -0.53 to 0.01, p = 0.06).

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close to significanceno p-value reported

However, we found a close to significance trend for trials where the first author was a psychologist/social scientist to report more favorable outcomes for pharmacotherapy than studies where the first author was a psychiatrist/MD (b = -0.25, 95% CI -.51 to 0.01, p = 0.06).

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