Barely Significant
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Structural analysis and evolution of specificity of the SUMO UFD E1-E2 interactions.

Sci Rep · 2017 · PMC5292753 · PMID 28165030

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quite significantno p-value reported
Protein sequence variations in the E1 UFD domain of different UbL modifiers are quite significant, especially in the binding region to the E2 enzyme.

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