showed a trendP = 0.23
14 , 15 For thapsigargin-exposed iHCECs, oxotremorine treatment showed a trend for reduced ATF4 mRNA expression to 118.2 ± 43.7% ( P = 0.23) compared with untreated controls (148.3 ± 28.3%) and reduced CHOP mRNA expression to 112.3 ± 60.6% ( P = 0.024) compared with untreated controls (188.1 ± 8.0%; Fig. 7 A).