At the end of the experiment, 5-FU significantly reduced the tumor weight and volume of NC group, whereas the effects of 5-FU did not reach statistical significance in 125 m group, although it showed a reduced trend ( Fig. 6B ,C, S2).
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CXCL12/CXCR4 axis induced miR-125b promotes invasion and confers 5-fluorouracil resistance through enhancing autophagy in colorectal cancer.
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