nearly significantP = 0.079
For CA genotype carriers, tacrolimus C/D ratios were 191.6 ± 192.2, 159.3 ± 194.6, 158.7 ± 158.6, and 108.1 ± 96.8 For AA genotype carriers, tacrolimus C/D ratios were 76.6 ± 108.8, 9.2 ± 86.3, 65.9 ± 84.4, and 73.9 ± 110.3 The differences were significant at week 1, week 2, and week 3 ( P = 0.007, 0.018, and 0.019, resp.) and were nearly significant at week 4 ( P = 0.079).