Prospects and limitations of improving skeletal growth in a mouse model of spondyloepiphyseal dysplasia caused by R992C (p.R1192C) substitution in collagen II.

PLoS One · 2017 · PMC5300241 · PMID 28182776

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showed a trendno p-value reported

First, the number of samples available for morphometry that showed a trend toward shortening of bones was limited because only 12.5% of littermates expressed the three transgenes needed for the production of the R992C mutant.

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