highly significantP <0.001
Across the groups, an overall highly significant difference among treatments was detectable ( F = 61.600, P <0.001), mostly due to the fact that the patients receiving drugs alone had more symptoms than the two SLIT groups (Post Hoc Sidak correction: drugs vs. sSLIT, mean difference 142.3, P < 0.001; drugs vs. aSLIT, mean difference 147.4, P < 0.001).