Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.

This group showed a trend for wild-type BRAF and MACROD2 deletions (Fisher's exact test, P =0.01 and 0.02, respectively) and was associated with a specific DNA methylation pattern, namely cluster_4 ( P =0.0057, Chi-square test) ( Supplementary Fig. 10 ).

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