Cells subjected to 15 and 25 dyne cm -2 spent more time migrating with the flow ( Fig 1E ), but again data did not reach statistical significance.
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Flowtaxis of osteoblast migration under fluid shear and the effect of RhoA kinase silencing.
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MC3T3-E1 osteoblasts showed peak migration speed with the onset of the flow and had a decreasing trend thereafter.
There was an increasing trend of osteoblastic cell number recruited to migrate with the flow direction with increasing shear stress ( Fig 1D ) but not reaching statistical significance.