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High expression of cholesterol biosynthesis genes is associated with resistance to statin treatment and inferior survival in breast cancer.

Oncotarget · 2016 · PMC5312337 · PMID 27458152

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Sub-analyses of the prognostic importance of the signature and HMGCR in ER negative tumors did not reach statistical significance (data not shown) probably due to the less heterogeneous expression of these genes in ER negative tumors.

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