The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response.

plementary Figure S4 ).' Also in the Results section, the following sentence should have appeared with the two changes shown in square brackets: ‘Although the observed associations are not significant after correction for multiple testing of SNPs selected for these replication analyses, we observed marginally significant evidence of association of SNP rs11624702 in MDGA2 (MAM domain containing glycosylphosphatidylinositol anchor 2) with response in the ISPC alone ( P =0.061) and [‘and' should read ‘but not'] in the combined ISPC-AMPS-STAR*D meta-analysis ( P =0.029) [‘0.029' should read ‘0.36'], with the minor allele being associated with lower odds of response (that is, worse clinical outcomes)'.

also in 26,082 other papers

nificance but were in genes of biological interest, most notably NRG1, which merits further investigation into their potential role in depression and antidepressant response.' Also in the Discussion section, the following sentence should not have been included: ‘In particular, our analyses provided nominally significant evidence of association of SNP rs11624702 in MDGA2 with response in the combined ISPC-AMPS-STAR*D meta-analysis.'

also in 7,732 other papers