Departure from optimal O₂ level for mouse trophoblast stem cell proliferation and potency leads to most rapid AMPK activation.

Unlike the minimal effects that compound C had on the levels of ERRB and ID2 in cells cultured at 20% O 2 and 0.5% O 2 , both potency factors were reduced by compound C in cells at 2% O 2 (although the decrease in ERRB did not reach statistical significance).

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