High fat diet dysregulates microRNA-17-5p and triggers retinal inflammation: Role of endoplasmic-reticulum-stress.

World J Diabetes · 2017 · PMC5320749 · PMID 28265343

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highly significantno p-value reported

Changes in lipid profile and accumulation of free fatty acids are highly significant in all forms of diabetes pointing to its possible link with inflammation and vascular complications (reviewed in[ 26 ]).

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showed a trendno p-value reported

Indeed, treating the cells with PBA a general ER-stress inhibitor showed a trend decrease in TXNIP expression.

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