Altered pH gradient at the plasma membrane of osteosarcoma cells is a key mechanism of drug resistance.

Oncotarget · 2016 · PMC5325373 · PMID 27566564

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showed a trendno p-value reported

The alteration of ΔpH cm showed a trend of reduction in MG-63 cells and a significant reduction in Saos-2 sensitive (P-gp negative) cells when cells were treated with OME (Figure 5C ).

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