Mice, double deficient in lysosomal serine carboxypeptidases Scpep1 and Cathepsin A develop the hyperproliferative vesicular corneal dystrophy and hypertrophic skin thickenings.

PLoS One · 2017 · PMC5325571 · PMID 28234994

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showed a trendno p-value reported

ET-1 levels measured in the aqueous humour of CathA S190A /Scpep1 -/- mice showed a trend for increase as compared with WT mice ( S6 Fig ) but the difference was not statistically significant, consistent with results previously obtained for the blood plasma.

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