Exome Sequencing Identifies Potentially Druggable Mutations in Nasopharyngeal Carcinoma.

Sci Rep · 2017 · PMC5335658 · PMID 28256603

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showed a trendno p-value reported

Our mutational analysis also showed a trend towards an enrichment in the EGFR/PI3K/Akt/mTOR pathway where mutations in PIK3CA (n = 7), PLCG1 (n = 3), EGFR (n = 2), PTEN (n = 1), and PRKCZ (n = 3) were identified in ~15% of our sample cohort.

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