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Elevated Fibroblast growth factor 21 (FGF21) in obese, insulin resistant states is normalised by the synthetic retinoid Fenretinide in mice.

Sci Rep · 2017 · PMC5335663 · PMID 28256636

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FEN inhibited weight gain and adiposity (data not shown) in many Alb-cre- Ptp1b −/− mice but this did not reach statistical significance ( Fig. 3a ).

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