Inappropriate combination of warfarin and aspirin.

Although it did not reach statistical significance, there was a trend toward increased use of proton pump inhibitors in patients with a history of major bleeding (23.1% vs. 9.2%; p=0.098).

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Independent correlates of warfarin-aspirin therapy in patients with AF were found to be vascular disease (OR, 4.0; 95% CI, 1.9-8.5; p<0.001), diabetes (OR, 2.6; 95% CI, 1.2-5.8; p=0.02), and age (OR, 0.97; 95% CI, 0.94-1.00; p=0.065), although the latter had borderline significance.

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