Five studies [ 20 , 26 , 30 – 32 ] reported significantly improved MMSE scores after treatment (12 weeks of a traditional Chinese medicine [ 26 ]; 8 weeks of 60 mg/day nicergoline [ 20 ]; 12 weeks of 22.5 g/day TJ-47 Choto-san extract [ 30 ]; 12 weeks of 1.2 g/day bushen [ 31 ]; 12 weeks of 3/day Congrongyizhi capsules [ 32 ]) and another showed a trend towards improved MMSE scores following 8 weeks of 7.5 g/day of toki-shakuyaku-san powder [ 23 ].
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A Systematic Review of Intervention Studies Examining Nutritional and Herbal Therapies for Mild Cognitive Impairment and Dementia Using Neuroimaging Methods: Study Characteristics and Intervention Efficacy.
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