Immune Regulation of Intrahepatic Regulatory T Cells in Fibrotic Livers of Mice.

Med Sci Monit · 2017 · PMC5338567 · PMID 28235976

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did not reach statistical significanceno p-value reported

However, Tregs depletion resulted in an 39% increase in CD8 + T cells compared with fibrosis, but did not reach statistical significance ( n =7–8, Figure 2B, 2D ).

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an increasing trendno p-value reported

In the present study, the CD8 + T cells showed an increasing trend after Tregs depletion compared with hepatic fibrosis, suggesting that Tregs have an inhibitory effect on intrahepatic CD8 + T cells in liver fibrosis, but the latter is not the main target.

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