nominally significantP = 0.08
In a Cox Proportional Hazards model adjusting for gender and depression onset, RA PRS predicted autoimmune disorder hazard (HR = 1.15, 95% CI = 1.01–1.31, P = 0.03), with a nominally significant independent effect of depression status (HR = 1.31, 95% CI = 0.97–1.38, P = 0.08).