Predicting drug-drug interactions through drug structural similarities and interaction networks incorporating pharmacokinetics and pharmacodynamics knowledge.

J Cheminform · 2017 · PMC5340788 · PMID 28316654

Europe PMC DOI

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moderately significantno p-value reported

The definition of “moderate” on Drugs.com is that the combination is moderately significant in clinical applications and usually the combination should be avoided or may be used only under special circumstances.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.