Spectral computed tomography in advanced gastric cancer: Can iodine concentration non-invasively assess angiogenesis?

When stratified by clinical subgroups, both nIC-AP and nIC-VP were higher in patients with serosal involvement, lymph node metastasis, poor differentiation, and diffused Lauren type than in those with depth invasion under T4, nodal status N0, high and moderate differentiation, intestinal and mixed Lauren type, but these differences did not reach statistical significance. nIC-AP and nIC-VP showed statistically significant differences between differentiation categories ( P = 0.003, P = 0.001, respectively) and between Lauren subtypes ( P = 0.016, P = 0.006, respectively).

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