only marginally significantP = 0.072
Similarly, the frequency of mutational events around HSP1 was also significantly lower (positions 558–559, 0.31 variants per position, normalized to 10 bases; P = 0.045), although the reduced frequency of mutational events at the LSP was only marginally significant (position 427, 0.46 variants per position, normalized to 10 bases; P = 0.072).