Barely Significant
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Ion-pair recognition by a neutral [2]rotaxane based on a bis-calix[4]pyrrole cyclic component.

Chem Sci · 2017 · PMC5341206 · PMID 28451196

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quite significantno p-value reported
Taken in concert, these thermodynamic observations are quite significant because the binding processes occur in a nonpolar solvent (chloroform) that minimizes solvation effects and better approximates to a gas phase host–guest complexation process.

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