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Tumor specific mutations in TERT promoter and CTNNB1 gene in hepatitis B and hepatitis C related hepatocellular carcinoma.

Oncotarget · 2016 · PMC5342339 · PMID 27276713

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Higher mutation frequencies have been identified in HCV-related (53.6%) compared to HBV-related (41.7%) tumors, in patients with α-fetoprotein ≤20ng/ml (56.4%) versus those > 20ng/ml (43.1%), and in smaller tumors (52.7%) versus larger tumors (43.5%), however such differences did not reach statistical significance.

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