The effect of tranexamic acid in traumatic brain injury: A randomized controlled trial.

Chin J Traumatol · 2017 · PMC5343096 · PMID 28209450

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5 Analysis of a TBI sub-group ( n = 270) showed a trend toward less mortality with TA. 6 , 7 A systematic review demonstrated statistically significant reduction in ICH progression with TA and a non-statistically significant improvement of clinical outcomes in TBI patients. 8 To date, there has been no study to determine the extent of ICH expansion after TA administration and also the optimal dose of TA in TBI patients.

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