Integrative analysis of DNA copy number, DNA methylation and gene expression in multiple myeloma reveals alterations related to relapse.

Oncotarget · 2016 · PMC5348347 · PMID 27811368

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a negative trendno p-value reported

The pooled effect sizes of the four genes, CNN2, CD27, KLHDC1 and AKT3 ( P2RY8 was not included because of probe set disparity between arrays) showed a negative trend ( g < 0) indicating a significant underexpression in the relapse samples (Figure 6F ).

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