In Figure 1D , TgM9 showed a trend of fewer dysplastic lesions (2.2 ± 0.31) compared to their WT littermates (3 ± 1.09) in CAC, however the difference was not significant.
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Epithelial derived-matrix metalloproteinase (MMP9) exhibits a novel defensive role of tumor suppressor in colitis associated cancer by activating MMP9-Notch1-ARF-p53 axis.
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