However, further analysis of the samples grouped by the PAM50 subtype revealed that, in basal-type breast cancers, LMO2 expression tended to be higher in samples with lymph node metastasis than in those without, although this difference did not reach statistical significance (Δ x ̄=0.261, p =0.128, Figure 1B ).
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LMO2 promotes tumor cell invasion and metastasis in basal-type breast cancer by altering actin cytoskeleton remodeling.
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