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Aberrant regulation of RANKL/OPG in women at high risk of developing breast cancer.

Oncotarget · 2017 · PMC5354797 · PMID 28002811

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Women with a 3-5 CTCs also exhibited reduced serum RANKL/OPG ratios, though this reduction did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.