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25-Hydroxycholesterol is involved in the pathogenesis of amyotrophic lateral sclerosis.

Oncotarget · 2017 · PMC5355309 · PMID 28060747

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In a recent study of OHCs in ALS patients, levels of 25-OHC serum tended to be higher in ALS patients than controls, but this difference did not reach statistical significance [ 19 ], in contrast to our observations.

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