Although a reduction in epinephrine‐induced platelet aggregation was observed in participants who were homozygous for the rs12041331 minor allele (maximal platelet aggregation = 33.6, 64.0, and 60.8 for PEAR1 rs12041331 genotypes A/A, G/A, and G/G, respectively), this comparison did not reach statistical significance ( P = 0.14).
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Prospective Evaluation of Genetic Variation in Platelet Endothelial Aggregation Receptor 1 Reveals Aspirin-Dependent Effects on Platelet Aggregation Pathways.
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0.1400
0.1400