HBV quasispecies composition in Lamivudine-failed chronic hepatitis B patients and its influence on virological response to Tenofovir-based rescue therapy.

Sci Rep · 2017 · PMC5356183 · PMID 28303969

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nominally significantno p-value reported

The clonal analysis uncovered 20 amino acid substitutions in ORF-S that showed nominally significant difference in frequencies between LMV-failed and untreated patients.

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