Polymorphisms in the multidrug-resistance 1 gene related to glucocorticoid response in rheumatoid arthritis treatment.

Rheumatol Int · 2017 · PMC5357283 · PMID 28132103

Europe PMC DOI

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0.1000

closest p · 2.0× alpha

0.1000

boldest claim

The sentences

did not reach statistical significancep = 0.10so close (0.05 < p ≤ 0.1)

Mutant allele frequencies The observed allele frequency was lower than expected based on the general population; however, these differences did not reach statistical significance: 0.36 for T-allele of C1236T (0.43 expected, binominal test of proportion p = 0.10), 0.37 for A or T-allele of G2677AT (0.44 expected, p = 0.11), and 0.50 for T-allele C3435T (0.57 expected, p = 0.11).

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