Structure-guided development of a high-affinity human Programmed Cell Death-1: Implications for tumor immunotherapy.

Although Th1 cytokines IFN-γ and IL-12 p70 showed a trend towards more prominent increase after HA PD-1 Ig treatment, compared to anti-PD-L1 ( Fig. 3 E–F), these differences were not statistically significant. 3.7.

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