Multimodal MR-imaging reveals large-scale structural and functional connectivity changes in profound early blindness.

Finally, corresponding differences in gray and white matter morphometry between early blind and sighted controls can also be easily visualized confirming an overall trend for decreases in morphometry measures rather than increases (inner rings).

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In contrast, sighted controls showed a trend for greater interhemispheric functional connectivity, particularly between occipital-occipital, cingulate-cingulate, and parietal-parietal cortices ( Fig 5B ).

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