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Oxidative stress downstream of mTORC1 but not AKT causes a proliferative defect in cancer cells resistant to PI3K inhibition.

Oncogene · 2017 · PMC5362070 · PMID 27991931

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OCR was also significantly increased upon drug removal in G1 and G2; however, in G3 this increase did not reach statistical significance ( Figure 1e ).

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