Barely Significant
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Apremilast, an oral phosphodiesterase 4 inhibitor, improves patient-reported outcomes in the treatment of moderate to severe psoriasis: results of two phase III randomized, controlled trials.

J Eur Acad Dermatol Venereol · 2017 · PMC5363239 · PMID 27538241

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Mean change in SF‐36v2 PCS score, although numerically greater with apremilast than with placebo, did not reach statistical significance or the MCID threshold at Week 16 (Table 2 ).

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