E-cigarettes and flavorings induce inflammatory and pro-senescence responses in oral epithelial cells and periodontal fibroblasts.

E-cigarette vapors from BLU ® Magnificent Menthol flavor also showed a trend towards increased protein carbonylation but not significant compared to the control (Figure 1A–1B ).

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We found e-cig flavoring BLU ® Classic Tobacco (16 mg nicotine) and Magnificent Menthol (zero nicotine) showed an increasing trend in the levels of IL-8 release and a significant increase in the levels of PGE 2 release compared to the controls (Figure 4A ).

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