Activation of Ras-ERK Signaling and GSK-3 by Amyloid Precursor Protein and Amyloid Beta Facilitates Neurodegeneration in Alzheimer's Disease.

Levels of phosphorylated ERK1/2 (P-ERK) normalized to total ERK showed a trend toward increase but showed inconsistencies within disease states and did not reach significance compared with the levels in NAD samples ( Fig. 3 H , I , L ).

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