We confirmed the increased phosphorylation of Akt-S473 in Tspan8-silenced cells (Figure 5C, 5D ) whereas the increase in ERK1/2 phosphorylation did not reach statistical significance (Figure 5C, 5D ).
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Tetraspanin 8 is a novel regulator of ILK-driven β1 integrin adhesion and signaling in invasive melanoma cells.
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