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The Addition of Liquid Fructose to a Western-Type Diet in LDL-R<sup>-/-</sup> Mice Induces Liver Inflammation and Fibrogenesis Markers without Disrupting Insulin Receptor Signalling after an Insulin Challenge.

Nutrients · 2017 · PMC5372941 · PMID 28294959

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In addition, we calculated another surrogate index of insulin sensitivity, the HOMA-IR, and the results also pointed to lower insulin sensitivity, especially in the WF group compared to W, although it did not reach statistical significance (1.7 ± 0.6, 4.3 ± 3.6, 3.0 ± 1.1 and 5.9 ± 1.2, expressed as mean ± SEM, for C, F, W and WF groups).

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