However, after EP induction (day 0), RA groups showed a trend towards a reduction in paw swelling, while RA+EP maintained its volume, being only RA+EP group, in contrast to the control and EP groups until the end of the study ( Fig 2 - Figure A in S1 File ).
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Periodontitis increases rheumatic factor serum levels and citrullinated proteins in gingival tissues and alter cytokine balance in arthritic rats.
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